000664 - B6 Strain Details - The Jackson Laboratory
WEBAlthough this strain is refractory to many tumors, it is a permissive background for maximal expression of most mutations. C57BL/6J mice are resistant to audiogenic seizures, have a relatively low bone density, and develop age related hearing loss.
C57BL/6 - Wikipedia
WEBC57BL/6, often referred to as "C57 black 6", "B6", "C57" or "black 6", is a common inbred strain of laboratory mouse. It is the most widely used "genetic background" for genetically modified mice for use as models of human disease.
C57BL/6 Mice | Charles River - Charles River Laboratories
WEBThe C57BL/6 mouse is a multipurpose model that can be used for research into physiology, immunology, safety and efficacy, oncology and genetics, as well as mouse model creation. B6 mice are often preferred to other inbred mice in certain research disciplines such as metabolic research.
How The B6 Mouse Strain is Revolutionising Drug Discovery
WEBOct 2, 2017 · Understanding the B6 mouse, its origins, characteristics and potential is required to make full and appropriate use of this model in research and drug discovery. The B6 mouse is a versatile and powerful tool in preclinical research.
Aged C57BL/6J Mice - The Jackson Laboratory
WEBAged C57BL/6J mice have research applications that include immunology, cancer, longevity interventions, and biomarker studies. C57BL/6J is the most widely used inbred mouse strain and the first to have its genome sequenced.
Three ways a B6J mouse differs from B6N and why it should …
WEBYou can have your mice evaluated using the C57BL/6 Substrain Characterization Panel. B6 and B6N substrains differ genetically as a result of accumulated spontaneous mutations. Learn why it is important not to use different substrains interchangeably.
The History of Black 6 Mice | Charles River Laboratories
WEBThis blog examines how Black 6 (B6) mice have aided a century of basic research and drug discovery.
Experiments done in Black-6 mice: what does it mean? | Lab …
WEBApr 22, 2019 · The C57BL/6J (B6J) mouse was the first strain to have its genomic sequence published, and this strain is considered a gold standard in many research areas.
The blessings and curses of C57BL/6 substrains in mouse genetic …
WEBThe C57BL/6 (B6) mouse strain is the most widely used strain in biomedical research, with nearly 25,000 articles on Pubmed documenting its use. Nearly half of these articles cite the use of C57BL/6J (B6/J), the original B6 strain from the Jackson Laboratory (JAX) from which all other B6 substrains were derived.
B6 Albino Mouse | Charles River - Charles River Laboratories
WEBThe B6 albino strain is a spontaneous albino mutant coisogenic C57BL/6 strain. The mice contain a mutation in the tyrosinase gene, and when homozygous for the mutation the coat color of the mice is albino rather than black. To Charles River in 2009 from NCI.
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