000651 - BALBc Strain Details - The Jackson Laboratory
WEBKey traits include a susceptibility to developing the demyelinating disease upon infection with Theiler's murine encephalomyelitis virus. The BALB/cJ substrain is susceptible to <i>Listeria</i>, all species of <i>Leishmania</i>, and several species of <i>Trypanosoma</i>, but is resistant to experimental allergic orchitis (EAO).
BALB/c - Wikipedia
WEBBALB/c is an albino, laboratory-bred strain of the house mouse from which a number of common substrains are derived. Now over 200 generations from New York in 1920, BALB/c mice are distributed globally, and are among the most widely used inbred strains used in animal experimentation .
BALB/c Mice | Charles River
WEBThe BALB/c model can be used to identify genes that determine susceptibility to infectious and neoplastic diseases. BALB/c mice is also known for being relatively resistant to diet-induced atherosclerosis, making them ideal for cardiovascular research.
C57BL/6 and BALB/c Mouse Models | Cyagen
WEBMar 30, 2020 · In C57BL/6 mice, Th1 immune response and IFNγ production play the key role. Alternately, it is easier to induce Th2 immune response in BALB/c mice, which is very common in infectious diseases and allergic reactions. BALB/c mice tend to produce a stronger humoral response than C57BL/6 mice.
WEBBALB/cJ mice are frequently used for a variety of immunological studies, in part because they demonstrate TH2- biased immune responses. BALB/c mice are particularly well known for the production of plasmacytoma on injection with mineral oil, forming the basis for the production of monoclonal antibodies. Mammary tumor incidence is
Clinical hematological and biochemical parameters in Swiss, BALB/c ...
WEBDec 18, 2020 · Our study sought to establish values to serve as reference values in various hematological and biochemical of serum parameters in mice of the Swiss (heterogeneous), BALB/c and C57BL/6 (isogenic) and B6D2F1 (hybrid) lineages, to guide researchers in the best choice of an experimental model.
BALB/c Mouse Models | Cyagen
WEBMar 18, 2020 · BALB/c is a laboratory-bred, albino strain of the house mouse, characterized by its immunodeficiency and extreme susceptibility to carcinogens. BALB/c mice are among the most widely used mouse strains across oncology, immunology, and nuclear medicine research, and are often the first option for animal experimentation models in …
The BALB/c Mouse: Genetics and Immunology | SpringerLink
WEBThese characteristics have made the BALB/c mouse a model for identifying genes that determine susceptibility to infectious and neoplastic diseases. In 1985 the laboratory BALB/c mouse became 72 years old. The current filial generations are somewhere around 350 generations [MURPHY].
The BALB/c Mouse Model for the Evaluation of Therapies to Treat ...
WEBMar 3, 2023 · With respect to therapeutic evaluation, the BALB/c mouse model is a robust model of infection, typically using females 6–8 weeks old (Table 1). A target dose of approximately 20–50 LD 50 equivalents achieves an acute, lethal infection.
BALB/c Mice - Charles River Laboratories
WEBThe BALB/c model can be used to identify genes that determine susceptibility to infectious and neoplastic diseases. BALB/c mice is also known for being relatively resistant to diet-induced atherosclerosis, making them ideal for cardiovascular research.
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