Evaluation of the anti-cancer efficacy of lipid nanoparticles ...
WEBFeb 16, 2024 · A xenograft model was made using CaSki cells in BALB/c nude mice. To evaluate anticancer efficacy, mice were grouped. ENB101-LNP was given three times weekly for 3 weeks intravenously, and cisplatin was given once weekly intraperitoneally.
Evaluation of the anti-cancer efficacy of lipid nanoparticles ...
WEBFeb 16, 2024 · We evaluated the efficacy of ENB101-LNP and cisplatin using a xenograft model of cervical cancer by subcutaneously injecting CaSki cells into the right thigh of BALB/c nude mice. The mice were divided into different groups and received the drugs according to specific dosages and administration schedules outlined in Fig 2A .
M1 macrophage-membrane-cloaked paclitaxel/β-elemene …
WEBAll female BALB/c nude mice (6–8 weeks) were provided by Beijing Vital River Laboratory Animal Technology Co., Ltd. (Beijing, China) and were reared in a freedom environment. After one week, CaSki cells (1 × 10 6 ) were subcutaneously injected into the right flank of mice under anaesthetic.
CD38 symmetric dimethyl site R58 promotes malignant tumor cell …
WEB1 day ago · Transfected tumor cells (3×10ˆ6) were subcutaneously injected into female BALB/c nude mice in a volume of 200 μL. Measurements of tumor size and body weight were recorded on indicated dates, with tumor volume calculated as length × widthˆ2 × (π/6). ... Immunopurification of cell extracts of CaSki cells expressing Flag-CD38 using an anti ...
Reversal of the Malignant Phenotype of Cervical Cancer CaSki …
WEBApr 11, 2006 · To address this question, CaSki cells transfected either with AAV-Laz or AAV-HPV16E7AS were injected into the buttocks of nu/BALB-c mice subepidermally, and the tumorigenicity rate was determined by successively observation.
CKD-602, a topoisomerase I inhibitor, induces apoptosis and cell …
WEBMay 28, 2019 · CaSki cells were subcutaneously injected into BALB/c-nude mice and cervical cancer xenograft model was established to elucidate the antitumor effect of CKD-602 in vivo. Treatment with CKD-602 induced apoptosis and increased expression of the enzyme PARP, cleaved PARP, and BAX.
Schisandrin B synergizes docetaxel-induced restriction of growth …
WEBJul 8, 2020 · The effects of Sch B in cervical cancer were further confirmed in Caski cell-xenograft BALB/c nude mice. Co-administration of Sch B enhanced the anti-tumor effects of DTX in vivo, inhibited tumor formation, increased apoptotic cells, and reduced Ki67 and N-cadherin expression.
P3AE5K efficacy in a xenograft model. BALB/c nude mice bearing CaSki …
WEBBALB/c nude mice bearing CaSki cell‐derived xenografts were intraperitoneally injected with DMSO or 3 mg/kg of P3AE5K (n = 6/group) once a week for 4 wk (A).
HPV-16 E6/E7 promotes cell migration and invasion in ... - Springer
WEBJun 21, 2015 · Immunohistochemical evaluation of E-cadherin and P-cadherin expressions in cancerous tissues of BALB/c-nu mouse model. We constructed a BALB/c-nu mouse model which was inoculated with Siha and Caski cells stable transduced by HPV-16 E6/E7 promoter-targeting siRNAs or scrambled siRNA.
Antitumor efficacy of CKD-602 in a CaSKi xenograft model
WEBGroups of BALB/c-nude mice (five per group) were subcutaneously injected with CaSki cells and then treated (intravenously) with CKD-602 (25 m/ kg) or PBS two weeks after the transplantation,...
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