C57BL/6 and BALB/c Mouse Models | Cyagen
WEBMar 30, 2020 · In C57BL/6 mice, Th1 immune response and IFNγ production play the key role. Alternately, it is easier to induce Th2 immune response in BALB/c mice, which is very common in infectious diseases and allergic reactions. BALB/c mice tend to produce a stronger humoral response than C57BL/6 mice.
C57BL/6 - Wikipedia
WEBC57BL/6, often referred to as "C57 black 6", "B6", "C57" or "black 6", is a common inbred strain of laboratory mouse. It is the most widely used "genetic background" for genetically modified mice for use as models of human disease.
Immunodeficient Mice for Cancer Studies: Which host strain …
WEBJAX maintains live colonies of three different nude strains: NU/J inbred mice, B6-nude congenic mice, and J:NU outbred nudes. Being inbred and congenic, respectively, NU/J and B6-nudes are genetically homogeneous. Therefore, they are likely to support more consistent tumor growth.
WEBStrain Common Names: B6, Black 6, C57 Black Type: Inbred. Characteristics. Low susceptibility to tumors. High susceptibility to diet-induced obesity, moderate hyperglycemia and hyperinsulinemia. High susceptibility to diet-induced atherosclerosis. High incidence of hydrocephalus and malocclusion.
A Contrast in Pathogenic Responses between C57BL/6J and BALB…
WEBIn bacterial keratitis models, B6 mice are susceptible, whereas BALB/cJ (BALB/c; type 2–dominant) mice exhibit a resistant phenotype. As such, we questioned whether the type 1/type 2 paradigm could be extrapolated to events associated with retinal pathogenesis.
Comparison of BALB/c and B6-albino mouse strain blastocysts as hosts ...
WEBOur data suggest that BALB/c is a suitable blastocyst host strain for C2 ES cells and has an advantage over the B6-albino strain for receiving the injection of C2 ES cells.
Elucidating different pattern of immunoregulation in BALB/c
WEBJan 15, 2021 · In the current study we compare the hierarchy of immunoregulatory pathways in BALB/c, C57BL/6 mice and their F1 progeny (BALB/c × C57BL/6). Using multicolor flow cytometry, we show that S....
Differences between C57BL/6 and BALB/cBy Mice in Mortality and …
WEBFor instance, NSV infection of C57BL/6 mice (B6) causes fatal disease after i.c. inoculation of virus while BALB/cBy mice (By) generally survive infection ( 20 ). The reasons for differences in mouse genetic susceptibility to NSV are not known.
Complete elucidation of a minimal class I MHC natural killer cell ...
WEBJun 2, 2005 · Ligand identification studies using soluble class I MHC tetramers have shown that the specificities of the B6 and BALB/c alleles of Ly49A are similar, but differential killing of H-2D d+...
Enhanced protection of C57 BL/6 vs Balb/c mice to melanoma …
WEBDec 26, 2017 · Balb/c mice are highly susceptible to B16F10 liver metastasis compared to C57 BL/6 mice. (A-C) Balb/c mice (Bc) received intrasplenic injections of 100,000 B16F10luc cells (“100 k”), whereas C57 BL/6 mice (B6) received either 100,000 or 300,000 cells (“100 k” or “300 k”).
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