Rat Genome Database
WEBRGD is a comprehensive resource for rat genomic data, annotation, and analysis. Find out the latest news on RGD, including the release of GRCr8, a new rat reference assembly, and explore various tools for genome visualization, enrichment, and pathway exploration.
Progress and prospects in rat genetics: a community view
WEBApr 28, 2008 · The rat is an important system for modeling human disease. Four years ago, the rich 150-year history of rat research was transformed by the sequencing of the rat genome, ushering in an era of...
Rat genetics: attachign physiology and pharmacology to the …
WEBJan 1, 2002 · Through the study of comparative genomics, physiological, genetic and phenotypic data from the rat and mouse model organisms can be used to inform studies of human disease by providing...
Rat genetics: attaching physiology and pharmacology to the …
WEBCombined with the wealth of physiological and pharmacological data for the rat, the genome sequence should facilitate the discovery of mammalian genes that underlie the physiological pathways that are involved in disease.
Rat models of human diseases and related phenotypes: a …
WEBAug 2, 2020 · This article summarizes the progress in identifying rat genes underlying human diseases and related phenotypes, using positional and reverse genetic approaches. It provides an inventory of over 350 rat genes with functional and disease relevance, and discusses the advantages and limitations of rat models.
A revamped rat reference genome improves the discovery of genetic …
WEBMar 26, 2024 · Systems genetics in the rat HXB/BXH family identifies Tti2 as a pleiotropic quantitative trait gene for adult hippocampal neurogenesis and serum glucose.
Genome-to-phenome research in rats: progress and perspectives
WEBJan 1, 2021 · The significantly improved rat reference genome with its augmented structural accuracy and contiguity is evolving to full annotation with collection and characterization of genome-wide DNA variants for genetic analysis with health and disease phenotypes.
The Rat Genome Database: Genetic, Genomic, and Phenotypic …
WEBJun 23, 2023 · The Rat Genome Database (RGD, https://rgd.mcw.edu) is a model organism database that provides access to a wide variety of curated rat data including disease associations, phenotypes, pathways, molecular functions, biological processes, cellular components, and chemical interactions for genes, quantitative trait loci, and strains.
What everybody should know about the rat genome and its online ...
WEBThe website includes pages describing each rat gene and its function; an extensive catalog of rat strains used as experimental models, with their phenotypes and known diseases; and all rat...
2022 updates to the Rat Genome Database: a Findable, Accessible ...
WEBMar 17, 2023 · RGD is a public source of rat genetic, genomics, and phenotypic data, with data for human and other model organisms. RGD provides tools for data mining, analysis, and visualization, and follows FAIR data principles for …