Laboratory mouse - Wikipedia
WEBMost laboratory mice are hybrids of different subspecies, most commonly of Mus musculus domesticus and Mus musculus musculus. Laboratory mice can have a variety of coat colours, including agouti, black and albino. Many (but not all) laboratory strains are inbred.
000058 - Strain Details - The Jackson Laboratory
WEBThis unique characteristic makes these mice ideal for creation of novel strains with targeted mutations (gene knockouts). B6 albino mice are used to generate blastocysts that can be used for microinjection of genetically modified C57BL/6J embryonic stem cells.
Laboratory Mice and Rats - labome.com
WEBDec 25, 2023 · Albinism of laboratory rodents: The majority of laboratory rodents are albinos, due to a common mutation in tyrosinase gene in all albino laboratory rat strains [18] and in at least some of the albino mouse strains [19]. Tyrosinase is the rate-limiting enzyme in the production of melanin pigment.
WEBBALB/cJ mice are frequently used for a variety of immunological studies, in part because they demonstrate TH2-biased immune responses. BALB/c mice are particularly well known for the production of plasmacytoma on injection with mineral oil, forming the basis for the production of monoclonal antibodies. Mammary tumor incidence is normally low ...
BALB/c - Wikipedia
WEBBALB/c is an albino, laboratory-bred strain of the house mouse from which a number of common substrains are derived. Now over 200 generations from New York in 1920, BALB/c mice are distributed globally, and are among the most widely used inbred strains used in animal experimentation. [1]
MGI - Biology of the Laboratory Mouse - The Jackson Laboratory
WEBThe widely distributed Swiss albino mice, largely noninbred, are mainly derived from two males and seven females which Clara J. Lynch of the Rockefeller Institute obtained from A. de Coulon of Lausanne in 1926 (Lynch, 1961, personal communication). The original stock probably came from Paris.
Albino Mouse - an overview | ScienceDirect Topics
WEBIn particular, Balb/c mice (albino, immunodeficient laboratory-bred strain) treated with fucoidans over 4 days have reduced parasitemia over the treatment, hypothesizing the inhibition of the adhesion and interaction between merozoites and RBC by the direct binding of the function group containing the sulfate to the host cells, and thus ...
Light and the laboratory mouse - ScienceDirect
WEBApr 15, 2018 · In this review, we will summarise the visual and non-visual systems of the laboratory mouse, including the retinal photoreceptors that mediate these responses, differences in common laboratory strains and practical recommendations for rodent husbandry and research.
Albino Mouse - an overview | ScienceDirect Topics
WEBThe development of inbred strains of laboratory mice was central to mouse genetics because inbred strains enabled the genetic analysis of individual mutations and traits by eliminating the ‘noise’ of heterogeneous segregating genetic backgrounds.
The Tyr (albino) locus of the laboratory mouse | Mammalian …
WEBTyrosinase is encoded at the albino (Tyr) locus of the mouse on Chromosome 7 (Kwon et al. 1989b), where multiple natural mutations and manmade mutations (Fig. 1) have helped to define the functions and interactions of this enzyme with other proteins that together effect normal pigmentation.
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