The two El Clásicos of the season will take place at similar dates to 2024–25, with Barcelona going to the Santiago Bernabéu in late October, before hosting Real Madrid at the Camp Nou on May 10th in what could be a title decider. The Catalan derbies vs. Espanyol are scheduled to be played in January and April.

La Liga's fixture list for the upcoming season confirms Barcelona will play their first three matches of the league season away from home.

The duel between Real Madrid and Barcelona will return with two high-tension clashes: the first leg will be played at the Santiago Bernabéu, on the 10th matchday (October 26), while the return is scheduled for the 35th matchday, on May 10, at the renovated Spotify Camp Nou.