For many people who have bipolar I, lithium is that most elusive of pharmacological treatments, the “magic bullet”—a single intervention that completely eliminates the symptoms of a disease. Since the ...

Can lithium’s effect on daily activity patterns reveal who will benefit from treatment? A six-week trial finds circadian shifts emerge early, before mood improves, hinting at a biological clue to ...

Six predictors could help determine the amount of lithium needed to treat patients with bipolar disorder, according to a large study led by researchers at Karolinska Institutet in Sweden. The study, ...

Lithium carbonate and valproate sodium are each recommended as monotherapy for preventing relapses in patients with bipolar disorder and are sometimes used in combination. However, combination therapy ...

Changes Clinical Practice: Based on this large trial, lithium alone or a lithium-valproate combination should be used as first-line maintenance treatment for bipolar affective disorder type I instead ...

Lithium is associated with an increased risk for thyroid dysfunction and chronic kidney disease (CKD) in patients with incident bipolar disorder (BD), according to a study published online Feb. 11 in ...

Compared with lithium, valproate, olanzapine, quetiapine, and risperidone generally exhibited a lower likelihood of thyroid dysfunction. HealthDay News — Lithium is associated with an increased risk ...

While lithium treatment has proven to be a godsend for many of the two million Americans with bipolar disorder, it is not without its downside. People on the drug may develop hypothyroidism, tremors, ...

Since 1949, lithium has been a mainstay for treating bipolar disorder (BD), a mental health condition marked by extreme mood swings. But scientists still don't have a clear understanding of how the ...

Six predictors could help determine the amount of lithium needed to treat patients with bipolar disorder, according to a large study led by researchers at Karolinska Institutet in Sweden. The study, ...