New findings reveal how cancer manipulates immune pathways and highlight therapeutic strategies to unleash T-cells against even the most resistant tumors. Study: Cancer cells impair monocyte-mediated ...

Cutaneous squamous-cell carcinoma (SCC) is primarily caused by oncogenesis mediated by ultraviolet radiation, and β-human papillomavirus (β-HPV) is believed to be a mere facilitator that is ...

Donor-Specific B Cells in Transplantation. The major goal of this project is to determine the properties of donor-specific B cells in recipients that maintain stable graft function and in those that ...

A man with long-standing type 1 diabetes underwent transplant with UP421 gene-edited islet cells designed to avoid rejection. Even without immunosuppression, the patient remained free of an immune ...