TNAP is a membrane-bound ectoenzyme that hydrolyzes PP i, creating a pro-mineralization milieu. 10 TNAP is expressed by mineralizing cells, e.g. osteoblasts, odontoblasts and chondrocytes.
Zweifler, Laura E., Patel, Mudita K., Nociti, Francisco H., Wimer, Helen F., Millán, Jose L., Somerman, Martha J., and Foster, Brian L. 2015. "Counter-regulatory ...