Toll-like receptor 3 (TLR3) is a pattern recognition receptor mainly known for its role in innate immune response to infection. Indeed, binding of double-stranded RNA (dsRNA) to TLR3 triggers a ...

C-Type lectin receptors (CLRs) constitute a family of pattern recognition receptors expressed primarily on myeloid cells that detect carbohydrate moieties on fungal cell walls. Through recognition of ...

Triple-negative breast cancer has long been one of the most stubborn targets in oncology. Lacking the estrogen receptor, ...

Newswise — Plants detect fragments released from microbes through pattern recognition receptors at the cell surface. Chitin, a major component of fungal cell walls, is well known to activate plant ...

Nanyang Technological University, Singapore (NTU Singapore) scientists have developed a way to "supercharge" a plant's ...

The innate immune system is the body's first line of defense against pathogens and foreign substances. An essential component of this system are pattern recognition receptors, which recognize non-self ...

Innate immune sensors—known as pattern recognition receptors (PRRs)—detect specific molecular components of bacterial or viral intruders. The PRRs forward the signals which results in the production ...

After identifying a novel population of innate lymphoid cells in the gut, Gregory Sonnenberg set out to characterize these ...

A team involving researchers from Wroclaw Medical University analyzed studies of people with schizophrenia spectrum disorders and mood disorders, including depression and bipolar disorder. They found ...

He began searching for novel parasite-fighting immune cells. McKenzie knew that IL-25 triggers a class of T cells called type-2 helper T cells (Th2s) to proliferate and produce IL-13, and he wondered ...

When a virus slips into a human cell, the first hours of infection decide much of what follows. The cell’s pattern ...

The immune system may also play a role in mental disorders. Scientists are investigating these links with brain function in greater detail, and new findings show that immune changes may differ by ...