Medically reviewed by Smita Patel, DO Key Takeaways Lissencephaly is a rare genetic condition that makes the brain smoother ...

Lissencephaly means “smooth brain.” It is a brain abnormality wherein the brain’s outer layer has fewer folds. Conditions that can cause lissencephaly include Miller-Dieker syndrome and Walker-Warburg ...

Lissencephaly is a rare condition that causes a child’s brain to develop the wrong way during pregnancy. A child with the disorder may have an unusual-looking face or a hard time swallowing, among the ...

Lissencephaly is a rare congenital developmental disease that can be caused by, amongst other anomalies, a mutation of the DCX gene. Affected individuals are born with serious developmental ...

Lissencephaly is a condition that causes the cerebral cortex of the brain to become abnormally smooth, which results in a multitude of symptoms including facial malformations and even seizures.

Lissencephaly represents a term for a spectrum of severe and rare brain malformations caused by a failure in the migration of neurons that were supposed to reach designated positions in the cerebral ...