(A) scRNA-seq with ST can reveal spatial zonation profiles of gene expression in the normal liver and a detailed cell landscape of the human liver, showing that 50% of liver genes have partitioning ...

Chronic liver damage can lead to hepatitis, which causes fibrosis of the liver. This buildup of collagen and other fibrous tissue accelerates when hepatic stellate cells become activated during ...

Until now, doctors knew hepatic stellate cells mainly as drivers of liver fibrosis. The actual functions of this cell type have hardly been studied to date. Researchers have now determined that ...

CYR61, cysteine-rich angiogenic inducer 61; FT, factors of transcription; LATS, large tumor suppressor; MOB, mob kinase activator; MST, mammalian sterile 20-like ...

The aging liver undergoes dramatic changes in its functional organization and other key attributes, which may underpin its increasing susceptibility to disease, according to a study led by ...

The liver stands as a powerhouse organ, orchestrating a symphony of crucial functions essential for our overall health. It serves as the body’s primary detoxifier, meticulously removing harmful ...

An asthma drug called formoterol may help reverse MASH-related liver damage, prompting new clinical trials after promising ...

The liver and pancreas are organs in the upper abdomen. The liver is vital for metabolism, detoxification, digestion, and more. The pancreas produces essential enzymes and hormones. Together, they ...

Liver enzymes can fluctuate due to factors like hormonal changes or reactions to medications. Fluctuations are often temporary, but long-term changes may indicate a condition that requires medical ...