Thomas Müller’s Vancouver Whitecaps visit the Portland Timbers to kick off the Cascadia Cup.

The Major League Soccer season is fully underway, and we’re back with a new set of moneyline picks for the Week 3 slate. We have 14 Major League Soccer matches this weekend, headlined by the opening ...

The 2026 MLS season is underway. Lionel Messi will hope to lead Inter Miami to a repeat MLS Cup championship while securing a ...

Inter Miami’s visit to LAFC headlines the opening weekend.

USA TODAY Network's soccer experts predict the 2026 MLS season, including the MLS Cup winner, playoff teams, MVP, and Golden Boot.

The Florida derby and first all-Canadian clash highlight the second week of MLS.

The Eastern Conference will be extremely competitive in 2026.

Major League Soccer becomes the latest league to team up with a prediction platform as professional sports continue to look for new engagement opportunities for audiences. The deal aims to push MLS ...

With the 2026 Major League Soccer season kicking off this weekend, we surveyed USA TODAY Network's team of soccer experts for their predictions on how the new season will shake out. Feb. 21, 2026: ...