NFL Week 16 predictions by Microsoft Copilot AI for every game

Microsoft Copilot earned double-digit wins picking NFL games last week. Can the AI chatbot find similar success with its Week 16 NFL picks?

Self-learning AI releases NFL picks, score predictions every Week 16 game

For Week 16 NFL betting, SportsLine AI has evaluated the NFL odds and provided NFL betting picks for all 16 games. You can only see the AI predictions for the Week 16 NFL schedule here. After analyzing every game in Week 16, the AI says the Broncos (-3.5, 46.5), who have won 11 in a row, cover comfortably against the Jaguars .
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NFL Draft Prospects in the 2025 Xbox Bowl

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NFL best bets for Week 16: Trust the Eagles, fade the Broncos

A short week sets the tone with a rivalry game that could swing a division race followed by a Saturday matchup where one team’s ability to control the middle of games will be tested. Sunday brings a prove-it spot for a fading offense,

NFL Week 16 picks: Broncos edge Jaguars; 49ers defeat Colts

Sam Farmer makes his picks and score predictions for Week 16 of the NFL season, with the Rams sweeping the Seahawks and the Broncos extending their winning streak.

NFL Week 16 best bets, odds, predictions: Bears vs Packers, Colts vs 49ers, Allen, Montgomery props, more!

Here are my five best bets for the Week 16 slate. Be sure to check out DraftKings for all the latest game odds & team props for every matchup this week on the NFL schedule! Packers at Bears (-1.5): O/U 46.