Scleroderma, also known as systemic sclerosis, is a group of rare diseases that involve the hardening and tightening of the skin. It also may cause problems in the blood vessels, internal organs and ...

Researchers found a unique immune cell plays a key role in the chronic inflammation and scarring in the lungs and skin of people with scleroderma, or systemic sclerosis. After injecting mice with ...

Two new studies led by researchers at Hospital for Special Surgery (HSS) have uncovered key biological mechanisms driving systemic sclerosis (SSc), or scleroderma – a rare and often devastating ...

A team of researchers at the Medical University of South Carolina (MUSC) has found that the molecule lysyl oxidase (LOX) plays a number of important roles in promoting skin and organ fibrosis in ...

Like many autoimmune diseases, systemic sclerosis, or scleroderma, can be a challenge to diagnose because its symptoms are varied, can range from mild to debilitating, and often resemble those of ...

Epigenetic drugs that have shown promise in cancer trials significantly reduce scarring in the cells of patients with scleroderma, a new study shows. Results reveal that drugs that inhibit BRD4, known ...

NEW HAVEN, Conn. (WTNH) — What is scleroderma, who does it affect and what are the treatments? Dr. Monique Hinchcliff, the ...

Although less common than other subtypes of systemic sclerosis (SSc), systemic sclerosis sine scleroderma (ssSSc) makes up more than 8% of SSc cases and "should not be neglected," according to a new ...

Systemic sclerosis (SSc), or scleroderma, is a chronic, multisystem autoimmune rheumatic disease characterized by exaggerated fibrosis, vasculopathy, and derangements of the immune system. When ...

When Dee Burlile was diagnosed with scleroderma in 2016, she didn’t know what it was or how to treat it. She quickly found out that she wasn’t alone. Scleroderma is a rare autoimmune condition that ...

Scleroderma renal crisis is often the most challenging type of scleroderma emergency to identify promptly, according to Francesco Boin, MD, professor of medicine and director of the scleroderma center ...

Investigators have discovered that a biodegradable nanoparticle used in medical sutures could combat a rare, sometimes-fatal autoimmune disease. Researchers found that a unique macrophage, an immune ...