Genetic variants that cause rare disorders may remain elusive even after expansive testing, such as exome sequencing. The diagnostic yield of genome sequencing, particularly after a negative ...

What is Third-Generation Sequencing? Third-generation sequencing, also known as long-read sequencing, refers to the latest advancements in DNA sequencing technologies that enable the analysis of ...

Antibodies are the immune system's precision tools for recognizing and neutralizing viruses, bacteria and other foreign ...

Due to its high accuracy and fast, simple workflow, capillary electrophoresis (CE) is a foundational technology for clinical applications. CE is an invaluable tool used to detect genetic variations ...

The study of genomic and transcriptomic information at the single-cell level has provided novel insights into various research areas, particularly cancer research. Traditional short-read sequencing, ...

Like sequencing technologies themselves, sequence analysis software has evolved substantially from its original incarnation. In the 1980s, before graphical operating systems became standard, these ...

The research team of Weihong Tan, Xiaohong Fang, and Tao Bing from the Hangzhou Institute of Medical Sciences, Chinese Academy of Sciences, proposed a ...

As high-throughput genomic sequencing generates increasing data volumes, researchers face challenges in identifying functional gene regions within DNA ...

A new study published in Addiction has identified genetic factors that influence both a person's risk of developing an addiction and their educational attainment. Researchers found that some genetic ...

Around 15% of hereditary diseases and cancers are associated with alternative RNA splicing, while the development of 1 in 6 cancers is driven by gene fusions. Isolating RNA from individual cells is a ...