After 10 years, members of the 4D Nucleome consortium have successfully completed the first phase of a project that aims to ...

Sometimes, a small error in the sequence of DNA can lead to a very serious disease. Scientists have identified many mutations ...

A new genetic mapping strategy reveals how entire networks of genes work together to cause disease, filling in the missing ...

Researchers at Duke University used CRISPR technologies to discover previously unannotated stretches of DNA in the ‘dark genome’ that are responsible for controlling how cells sense and respond to the ...

DNA's double helix has long stood as the symbol of life’s code. But buried within the genome lies a deeper level of complexity. One of the more intriguing discoveries in recent years is the i-motif—a ...

Researchers develop a groundbreaking genomic mapping to reveal how genes interact to cause diseases, paving the way for ...

Large-scale human genetics studies have shown that many risk variants for common and complex diseases sit in the non-coding ...

Researchers have developed a comprehensive atlas that maps DNA methylation—a critical chemical modification governing gene activity—across 39 human cell types, revealing a complex landscape of ...

DNA methylation is an epigenetic modification crucial to normal development, with its dysregulation leading to various diseases including cancer. As interest in epigenomics grows, an innovative ...