Poaching, excessive harvesting and other factors are endangering the slow-growing peyote plant, which is used in Indigenous prayer and ceremony.

Peyote is a sacred substance to many Indigenous peoples, but it's verging on endangered. A Scottsdale lab wants to fix that.

A study of the effects of peyote on American Indians found no evidence that the hallucinogenic cactus caused brain damage or psychological problems among people who used it frequently in religious ...

Peyote is being threatened by overharvesting, drug decriminalization laws and a resurgence in psychedelic use.

Indigenous people would struggle to access their sacred plant while seeing others use it in a way they deem profane, he said. Peyote supply remains limited for the Native American Church.

Peyote embodies the Creator’s spirit Darrell Red Cloud, who is Oglala Lakota, remembers at age 4 using peyote and singing ceremonial songs at all-night peyote ceremonies with his family.