Fresh off an endorsement from President Donald Trump, Rep. Julia Letlow of Louisiana is launching a U.S. Senate bid against fellow Republican and second-term Sen.

Rep. Julia Letlow announced Tuesday morning that she is running for Senate, after earning President Donald Trump's endorsement over the weekend for a Republican primary challenge against Sen.

Trump's endorsement of Rep. Julia Letlow over Sen. Bill Cassidy shakes up Louisiana's GOP Senate race, creating major headaches for Senate leadership.

President Trump is encouraging Rep. Julia Letlow to run against Republican Louisiana Sen. Bill Cassidy in the state's primary. CBS News' Caitlin Huey-Burns reports.

President Donald Trump’s decision to endorse a possible challenger against Sen. Bill Cassidy (R-LA) sent a jolt through GOP politics over the weekend, underscoring that no Republican incumbent is immune from presidential intervention,

Rep. Julia Letlow announced Tuesday she is running for Sen. Bill Cassidy's U.S. Senate seat after receiving an endorsement from President Donald Trump, The Advocate reported.

Louisiana Treasurer John Fleming has no plans to drop his Senate primary challenge against Sen. Bill Cassidy (R-LA) even after President Donald Trump preemptively endorsed another possible Republican contender.

President Donald Trump publicly endorsed Louisiana Rep. Julia Letlow (R-La.) for the U.S. Senate, urging her to enter the race and praising her as a proven conservative leader. Trump Backs Letlow For Louisiana Senate Run On Saturday,