When crossed to a strain expressing Cre recombinase, the Cre will excise a portion ... using electron microscopy (Kett et al., 2015). In this floxed mouse model, one loxP site is present upstream exon ...

The Wang lab is interested in brain estrogenic actions in the regulation of energy and glucose balance under different physiological conditions, including: Sex differences in response to nutritional ...

The Yong Xu lab is interested in novel neural circuits, neurotransmitters and intra-neuronal signals that are critical for coordinated control of metabolism and behavior. We generate unique mouse ...

Here, we generated an L cell-specific Cre mouse line for the first time by combination of the Flp-Frt and Cre-LoxP systems, which allows genetic manipulation specifically in the L cells and thus ...

LSEC isolated from Smo loxP/loxP transgenic mice that had been infected with adenovirus expressing Cre-recombinase to delete Smoothened showed over 75% knockdown of Smoothened. During culture, ...

Dysfunctional neurons in the cerebellum, a brain region that controls motor functions, reduced REM sleep in mice.

A central question in adult stem cell biology is elucidating the signaling pathways regulating their dynamics and function in diverse physiological and age-related contexts. Muscle stem cells in ...

Nik Dennler does not work for, consult, own shares in or receive funding from any company or organization that would benefit from this article, and has disclosed no relevant affiliations beyond ...

Whether you're after a comfortable all-in-one powerhouse or a flyweight pointer for fps, a Razer mouse can set you on a solid path to victory. These rodents come from a pedigree line of gaming ...