Nipocalimab-treated participants met the minimal clinically important improvement threshold for 84.5% of the 24-week period, compared with 38.7% for placebo-treated participants. Nipocalimab (Imaavy ™ ...

Earlier diagnosis of interstitial lung disease leads to gains in quality-adjusted life-years in all countries analyzed, with improvements ranging from 0.061 to 0.084 in the base case. The early ...

In 74 patients with IPF receiving antifibrotic therapy, sleep quality improved significantly, as the median Pittsburgh Sleep Quality Index score fell from 9 to 6. Patients with idiopathic pulmonary ...

Best practices most often mentioned by amyloidosis stakeholders included patient-centric multidisciplinary care, responsiveness to patients' questions, and timely intake of new patients who are at ...

Dual pathway blockade targets complement-driven pathology in AChR-positive MG, as well as FcRn-mediated pathogenic IgG recycling. Two patients with refractory anti-acetylcholine receptor (AChR) ...

After the enzyme-linked immunosorbent assay was added to the solid phase red cell adherence test, the detection rate of anti-CD36 increased about 15-fold. Platelet antibodies that may lead to fetal ...

Serif’s Modified DNA platform is engineered with carrier molecules and proprietary mRNA cofactors that enhance its activity and expression At the American Society of Gene and Cell Therapy (ASGCT) ...

Regenxbio announced plans to pursue accelerated FDA approval of RGX-202 and prepare for a potential commercial launch in 2027. The pivotal portion of the trial of RGX-202, a gene therapy for Duchenne ...

Recurrent atraumatic vertebral fractures warrant serum tryptase, KIT testing, and biopsy at augmentation. Indolent systemic mastocytosis (SM) should be suspected in patients presenting with atraumatic ...

In a cross-sectional study, the researchers reported psychiatric comorbidities in 46.5% of 43,270 adults with neurofibromatosis. The most common psychiatric comorbidities included mood disorders (22.1 ...

The model had an area under the receiver operating characteristic curve of 0.83 in a high-risk subgroup of patients with conditions that mimic ATTR-CM. An artificial intelligence model trained to ...

The high-output heart failure cohort was characterized by an increased frequency of secondary MF and lower baseline hemoglobin levels. Echocardiographic high-output heart failure in patients with ...