Injecting the RING-nanobody gene into mice with pathogenic tau, either directly into their brains or in their tails ...
A study uncovers how histone modifications, specifically in the H3.3 protein, regulate gene expression in mouse stem cells.
Departments of Pharmacology, UT Southwestern Medical Center, Dallas, USA Departments of Peter O’Donnell Jr. Brain Institute and Psychiatry, UT Southwestern Medical Center, Dallas, USA Department of ...
MDA5 is a critical cytoplasmic RNA sensor capable of triggering type I interferon pathways. This study shows that the E3 ...
Pathogenic activating point mutations in the LRRK2 kinase cause autosomal-dominant familial Parkinsońs disease (PD). In cultured cells, mutant LRRK2 causes a deficit in de novo cilia formation and ...
In a groundbreaking study published in Cell Metabolism00374-1), scientists have discovered that restricting the intake of a ...